[摘要]目的：研究分析胼胝体变性(MBD)患者的临床表现和影像学特征与诊断方法。方法：4例长期酗酒男性MBD患者，均经CT检查。结果：3例CT可见胼胝体膝部和压部对称性低密度病灶。1例CT表现为胼胝体膝部、体部、压部对称性低密度病灶。结论：CT为诊断胼胝体变性的主要手段，以胼胝体膝部、压部对称性病灶为其主要异常表现。

    [关键词] 胼胝体变性；计算机断层扫描；磁共振

    [中图分类号] R445 [文献标识码]A [文章编号]1674-4721(2009)05(a)-086-02

    Marchiafava-Bignami disease: an analysis of CT findings

    SONG Yang ,TAN Xiaotian

    (The Department of Radiology of Dalian Center Hospital，Dalian 116033，China)

    [Abstract] Objective：To study the CT findings of the patients with Marchiafava-Bignami disease(MBD), and discuss the diagnostic methods about MBD. Methods： 4 male patients with a long history of severe alcoholism had been diagnosed as MBDby means of neurological examination and CT scan. Results： In three cases CT revealed large low-density areas in the genu and the splenium of the corpus callosum. In one case CT revealed large low-density areas in the genu and the body and the splenium of the corpus callosum. Conclusion： CT is main effective modality for the diagnosing of MBD. The symmetrical lesions located in the genu and in the splenium of corpus callosum on CT are major angiographic abnormalities. ......