金天格胶囊在老年骨质疏松椎体压缩性骨折中的应用(1)
[摘要] 探讨金天格胶囊在老年骨质疏松椎体压缩骨折中的临床应用。选择2012年1月—2014年6月浙江省立同德医院住院治疗的69例老年骨质疏松椎体压缩性骨折患者，将患者按照随机数表法分为对照组及治疗组，对照组接受经皮球囊扩张椎体后凸成形术(PKP)治疗，治疗组则在对照组治疗方案的基础上加用金天格胶囊进行治疗。分别在术前进行访视并在术后3个月进行随访，观察并比较2组患者的椎体高度、Cobb′s、骨密度、视觉模拟评分(VAS)及Oswestry功能障碍指数。结果发现，与治疗前相比，2组患者在术后3个月随访时椎体高度、Cobb′s角、骨密度、VAS评分及Oswestry功能障碍指数均较治疗前显著改善(P<0.05);在治疗后3个月进行随访时，与对照组相比，治疗组骨密度较治疗前及对照组均显著升高(P<0.05)，椎体高度、VAS评分以及Oswestry功能障碍指数恢复更为明显(P<0.05)。基于以上结果可知金天格胶囊适用于骨质疏松椎体压缩性骨折PKP手术的辅助治疗，值得临床推广应用。
[关键词] 金天格胶囊;骨质疏松;椎体压缩性骨折
, 百拇医药
[收稿日期] 2014-10-07
[通信作者] 俞雷钧，副主任医师，研究方向为脊柱外科，E-mail：yuleijun326@sina.com
Application of Jintian′ge capsule in treatment of vertebral compression
fracture in senile osteoporosis patients
YU Lei-jun， WEN Jun-xia， SONG Hong-pu， LIU Hong
(Department of Orthopedics and Traumatology， Tongde Hospital of Zhejiang Province， Hangzhou 310012， China)
, 百拇医药
[Abstract] To study the clinical application of Jintian′ge capsule in treatment of vertebral compression fracture in senile osteoporosis patients. In the study， 69 senile osteoporotic vertebral compression fracture patients hospitalized in our hospital between January 2012 and June 2014 were selected and randomly divided into the control group and the treatment group. Patients in the control group were treated by percutaneous kyphoplasty (PKP)， while those in the treatment group were given Jintian′ge capsule in addition to PKP. Efforts were made to visit the patients before the surgery and in three month after that， observe and compared the vertebral height， Cobb′s angle， bone density， visual analogue scale (VAS) and Oswestry disability index between patients in the two groups. According to the findings， compared with before the treatment， patients in the two groups showed significant improvements in the vertebral height， Cobb′s angle， bone density， VAS and Oswestry disability index three months after the surgery (P<0.05); During the visit three months after the treatment， compared with the control group， the treatment group showed notable increases in all parameters (P<0.05)， particularly in the vertebral height， VAS and Oswestry disability index (P<0.05). Based on the above findings， Jintian′ge capsule is applicable in adjuvant therapy after the osteoporotic vertebral compression facture PKP surgery.
, 百拇医药
[Key words] Jintian′ge capsule; osteoporosis; vertebral compression fracture
doi：10.4268/cjcmm20150536
目前，随着我国老年人口比例的不断增加，已经逐步迈入老龄化社会，各种老年疾病的发病绝对人数及比例都在不断增加，需要引起足够的重视。骨质疏松是老年人群中常见的病理生理变化，而由此继发的骨质疏松性椎体压缩骨折则对老年患者的活动能力造成严重影响，导致其生活质量不断恶化。骨质疏松椎体压缩性骨折在60岁以上的老年人群中发病率较高，研究表明在骨质疏松椎体压缩骨折患者中，约有30%可出现明显的脊柱畸形、功能障碍以及严重腰背部疼痛等[1]。目前经皮球囊扩张椎体后凸成形术(PKP)已逐渐在临床上普及应用，提到了传统的长期卧床休息以及垫枕锻炼等疗法[2]。金天格胶囊为天然虎骨粉替代物，具有健骨强骨的功效[3]，在老年骨质疏松症中应用较广，而在骨质疏松椎体压缩性骨折中的应用还鲜见报道。本研究在采用PKP治疗老年骨质疏松椎体压缩性骨折的同时使用金天格胶囊进行辅助治疗，取得了较为满意的临床疗效，现报告如下。, 百拇医药(俞雷钧 闻君侠 宋红浦 刘宏)
[关键词] 金天格胶囊;骨质疏松;椎体压缩性骨折
, 百拇医药
[收稿日期] 2014-10-07
[通信作者] 俞雷钧，副主任医师，研究方向为脊柱外科，E-mail：yuleijun326@sina.com
Application of Jintian′ge capsule in treatment of vertebral compression
fracture in senile osteoporosis patients
YU Lei-jun， WEN Jun-xia， SONG Hong-pu， LIU Hong
(Department of Orthopedics and Traumatology， Tongde Hospital of Zhejiang Province， Hangzhou 310012， China)
, 百拇医药
[Abstract] To study the clinical application of Jintian′ge capsule in treatment of vertebral compression fracture in senile osteoporosis patients. In the study， 69 senile osteoporotic vertebral compression fracture patients hospitalized in our hospital between January 2012 and June 2014 were selected and randomly divided into the control group and the treatment group. Patients in the control group were treated by percutaneous kyphoplasty (PKP)， while those in the treatment group were given Jintian′ge capsule in addition to PKP. Efforts were made to visit the patients before the surgery and in three month after that， observe and compared the vertebral height， Cobb′s angle， bone density， visual analogue scale (VAS) and Oswestry disability index between patients in the two groups. According to the findings， compared with before the treatment， patients in the two groups showed significant improvements in the vertebral height， Cobb′s angle， bone density， VAS and Oswestry disability index three months after the surgery (P<0.05); During the visit three months after the treatment， compared with the control group， the treatment group showed notable increases in all parameters (P<0.05)， particularly in the vertebral height， VAS and Oswestry disability index (P<0.05). Based on the above findings， Jintian′ge capsule is applicable in adjuvant therapy after the osteoporotic vertebral compression facture PKP surgery.
, 百拇医药
[Key words] Jintian′ge capsule; osteoporosis; vertebral compression fracture
doi：10.4268/cjcmm20150536
目前，随着我国老年人口比例的不断增加，已经逐步迈入老龄化社会，各种老年疾病的发病绝对人数及比例都在不断增加，需要引起足够的重视。骨质疏松是老年人群中常见的病理生理变化，而由此继发的骨质疏松性椎体压缩骨折则对老年患者的活动能力造成严重影响，导致其生活质量不断恶化。骨质疏松椎体压缩性骨折在60岁以上的老年人群中发病率较高，研究表明在骨质疏松椎体压缩骨折患者中，约有30%可出现明显的脊柱畸形、功能障碍以及严重腰背部疼痛等[1]。目前经皮球囊扩张椎体后凸成形术(PKP)已逐渐在临床上普及应用，提到了传统的长期卧床休息以及垫枕锻炼等疗法[2]。金天格胶囊为天然虎骨粉替代物，具有健骨强骨的功效[3]，在老年骨质疏松症中应用较广，而在骨质疏松椎体压缩性骨折中的应用还鲜见报道。本研究在采用PKP治疗老年骨质疏松椎体压缩性骨折的同时使用金天格胶囊进行辅助治疗，取得了较为满意的临床疗效，现报告如下。, 百拇医药(俞雷钧 闻君侠 宋红浦 刘宏)